SAB5702986

Anti-Dystrophin Antibody

rabbit monoclonal, 10G10K7

• Synonym(e): BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85
• UNSPSC-Code: 12352203
• NACRES: NA.46
• Klon: 10G10K7, monoclonal
• application: IF; IHC
• Speziesreaktivität: mouse, rat
• Methode(n): immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200

Eigenschaften

• Produktbezeichnung: Anti-Dystrophin Antibody, clone 10G10K7, Rabbit Monoclonal,
• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Materialien: colorless
• Klon: 10G10K7, monoclonal
• Form: liquid
• Speziesreaktivität: mouse, rat
• Konzentration: 0.5mg/mL
• Methode(n): immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200
• Farbe: colorless
• Isotyp: IgG
• Immunogene Sequenz: LESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM
• UniProt-Hinterlegungsnummer: P11532
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... DMD(1756)

Beschreibung

Allgemeine Beschreibung

This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 3586-3685 of human Dystrophin (P11532).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Anwendung

IHC, IF/ICC

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1