SAB5702166

[KO Validated]Anti-ATG7 Antibody, clone 3X1W4, Rabbit Monoclonal

• Synonym(e): ATG7,APG7-LIKE,APG7L,GSA7,Apg7/Atg7
• UNSPSC-Code: 12352203
• NACRES: NA.46

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Materialien: colorless
• Klon: 3X1W4, monoclonal
• Form: liquid
• Mol-Gew.: 77 kDa
• Speziesreaktivität: rat, human, rat
• Konzentration: 1 mg/mL
• Methode(n): immunohistochemistry: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• Farbe: colorless
• Isotyp: IgG
• Immunogene Sequenz: MAAATGDPGLSKLQFAPFSSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPARLTLEFSAFDMSAPTPARCCPAIGTLYNTNTLESFKTAD
• UniProt-Hinterlegungsnummer: O95352
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... ATG7(10533)

Beschreibung

Allgemeine Beschreibung

This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Atg7(Apg7) (O95352).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Anwendung

WB, IHC, IP

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1