SAB5700854

Anti-HLA-E antibody produced in rabbit

• Synonym(e): EA1.2, EA2.1, HLA-6.2, HLA-E, QA1
• UNSPSC-Code: 12352203
• NACRES: NA.43
• Klon: polyclonal
• application: WB
• Speziesreaktivität: human
• Methode(n): western blot: 1:500-1:2000

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 40
• Speziesreaktivität: human
• Konzentration: 2.22 mg/ml
• Methode(n): western blot: 1:500-1:2000
• UniProt-Hinterlegungsnummer: P13747
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... HLA-E(3133)

Beschreibung

Allgemeine Beschreibung

HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HLA-E (NP_005507.3).

Physikalische Form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Lagerung und Haltbarkeit

Store at -20℃. Avoid freeze / thaw cycles.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable