SAB5700345

Anti-Phospho-STAT2-Y690 antibody produced in rabbit

• Synonym(e): IMD44, ISGF-3, P113, STAT113, STAT2
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 97
• Speziesreaktivität: rat, mouse, human
• Konzentration: 0.21 mg/ml
• Methode(n): western blot: 1:500-1:1000
• UniProt-Hinterlegungsnummer: P52630
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr690)
• Angaben zum Gen: human ... STAT2(6773)

Beschreibung

Allgemeine Beschreibung

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic phosphorylated peptide around Y690 of human STAT2 (NP_005410.1).

Physikalische Form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Lagerung und Haltbarkeit

Store at -20℃. Avoid freeze / thaw cycles.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable