SAB5700176

Anti-Symmetric DiMethyl-Histone H3-R2 antibody produced in rabbit

• Synonym(e): H3.4, H3/g, H3FT, H3t, HIST1H3A, HIST3H3, Histone H3
• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 15
• Speziesreaktivität: mouse, human, rat
• Konzentration: 0.45 mg/ml
• Methode(n): ChIP: 1:20-1:100; immunofluorescence: 1:50-1:200; immunohistochemistry: 1:50-1:200; immunoprecipitation (IP): 1:50-1:200; western blot: 1:500-1:2000
• UniProt-Hinterlegungsnummer: Q16695
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: dimethylation (Arg2)
• Angaben zum Gen: human ... H3-4(8290)

Beschreibung

Allgemeine Beschreibung

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Immunogen

A synthetic methylated peptide corresponding to residues surrounding R2 of human histone H3

Physikalische Form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Lagerung und Haltbarkeit

Store at -20℃. Avoid freeze / thaw cycles.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable