SAB5600106

Anti-Phospho-AMPA Receptor antibody, GluR 1 subunit (Ser845), Rabbit Monoclonal

recombinant, expressed in HEK 293 cells, clone RM296, purified immunoglobulin

• Synonym(e): Glutamate Receptor 1
• UNSPSC-Code: 12352203
• NACRES: NA.41
• Klon: RM296, monoclonal; recombinant monoclonal
• application: IHC; WB
• Speziesreaktivität: human
• Methode(n): immunohistochemistry: 1:100-1:200; western blot: 1:100-1:200
• citations: 3

Eigenschaften

• Rekombinant: expressed in HEK 293 cells
• Qualitätsniveau: 100
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: RM296, monoclonal; recombinant monoclonal
• Form: buffered aqueous glycerol solution
• Speziesreaktivität: human
• Methode(n): immunohistochemistry: 1:100-1:200; western blot: 1:100-1:200
• Isotyp: IgG
• NCBI-Hinterlegungsnummer: 2890
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer845)
• Angaben zum Gen: human ... GRIA1(2890)

Beschreibung

Allgemeine Beschreibung

GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) is located on human chromosome 5q33.2. It is expressed mainly in brain areas.

Spezifität

This antibody reacts to human Glutamate Receptor 1, AMPA Receptor (GluR1) only when phosphorylated at Ser845. There is no cross-reactivity to GluR1 that is not phosphorylated at Ser845. This antibody may also react to mouse or rat Phospho-AMPA Receptor (GluR1) (Ser845) as predicted by immunogen homology.

Immunogen

A phospho-peptide corresponding to human Phospho-Glutamate Receptor 1 (GluR1) (Ser845).

Biochem./physiol. Wirkung

GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) plays an important role in long-term potentiation (LTP). It is associated with migraine.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable