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SAB5300267

Sigma-Aldrich

Monoclonal Anti-Cytokeratin 5 antibody produced in mouse

clone 2C2, purified immunoglobulin, buffered aqueous solution

Synonym(e):

DDD, EBS2, K5, KRT5, KRT5A

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100

Konjugat

unconjugated

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

2C2, monoclonal

Form

buffered aqueous solution

Mol-Gew.

62.3 kDa

Speziesreaktivität

human, mouse, monkey

Methode(n)

direct ELISA: 1:10,000
flow cytometry: 1:200-1:400
immunohistochemistry: 1:200-1:1,000
indirect immunofluorescence: 1:200-1:1,000
western blot: 1:500-1:2,000

Isotyp

IgG1

NCBI-Hinterlegungsnummer

NM_000424

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... CK5(3852)

Immunogen

Purified recombinant fragment of human CK5 expressed in E.coli.
Mouse monoclonal antibody raised against CK5

Physikalische Form

Purified antibody in PBS with 0.05% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Stephen P Malkoski et al.
Molecular carcinogenesis, 53(10), 841-846 (2013-04-30)
Lung adenocarcinoma (AdC) and lung squamous cell carcinoma (SCC) are the most common non-small cell lung cancer (NSCLC) subtypes, however, most genetic mouse models of lung cancer produce predominantly, if not exclusively, AdC. Whether this is secondary to targeting mutations
Cristina Saiz-Ladera et al.
Oncogene, 33(37), 4599-4612 (2013-10-15)
The retinoblastoma gene product (pRb) controls proliferation and differentiation processes in stratified epithelia. Importantly, and in contrast to other tissues, Rb deficiency does not lead to spontaneous skin tumor formation. As the cyclin-dependent kinase inhibitor p21 regulates proliferation and differentiation
Michail Shipitsin et al.
Proteome science, 12, 40-40 (2014-07-31)
We have witnessed significant progress in gene-based approaches to cancer prognostication, promising early intervention for high-risk patients and avoidance of overtreatment for low-risk patients. However, there has been less advancement in protein-based approaches, even though perturbed protein levels and post-translational
Isaac O Karikari et al.
Journal of neurosurgery. Spine, 21(3), 386-393 (2014-06-07)
Chordoma cells can generate solid-like tumors in xenograft models that express some molecular characteristics of the parent tumor, including positivity for brachyury and cytokeratins. However, there is a dearth of molecular markers that relate to chordoma tumor growth, as well
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