SAB4700394

Monoclonal Anti-CD29 antibody produced in mouse

clone MEM-101A, purified immunoglobulin, buffered aqueous solution

• Synonym(e): Anti-ITGB1, Anti-Integrin β1 chain
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Konjugat: unconjugated
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: MEM-101A, monoclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human, pig, canine
• Konzentration: 1 mg/mL
• Methode(n): flow cytometry: suitable
• Isotyp: IgG1
• NCBI-Hinterlegungsnummer: NM_002211.3
• UniProt-Hinterlegungsnummer: P05556
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... ITGB1(3688)

Beschreibung

Allgemeine Beschreibung

Cluster of differentiation 29 (CD29), also known as integrin subunit β 1 (ITGB1), is a mechanosensor, encoded by the gene mapped to human chromosome 10p11.22. It is present in both normal cells and tumor-associated cells. The encoded protein has ubiquitous expression with a molecular mass of 130kDa.

The antibody MEM-101A reacts with CD29 (integrin beta1 chain), a 130 kDa single chain type I glycoprotein expressed as a heterodimer (non-covalently associated with the integrin alpha subunits 1-6). CD29 is broadly expressed on majority of hematopoietic and non-hematopoietic cells (leukocytes, platelets, fibroblasts, endothelial cells, epithelial cells and mast cells).

Immunogen

Raji Burkitt′s lymphoma cell line

Anwendung

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Flow cytometry/Cell sorting (1 paper)

Biochem./physiol. Wirkung

Cluster of differentiation 29 (CD29) acts as an adhesive molecule in the development of de novo focal contact, keratinocyte migration and re-epithelialization of wound tissue. CD29 with/without CD27 induce apoptosis, in association with a multifunctional protein galectin (Gal)-3.

Leistungsmerkmale und Vorteile

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Physikalische Form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable