SAB4504665

Anti-phospho-BL-CAM (pTyr⁸⁰⁷) antibody produced in rabbit

affinity isolated antibody

• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 95 kDa
• Speziesreaktivität: mouse, rat, human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:40000; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P20273
• UniProt-Hinterlegungsnummer: P20273
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr807)
• Angaben zum Gen: human ... CD22(933)

Beschreibung

Allgemeine Beschreibung

CD22 (cluster of differentiation 22) is a 140 kDa single-spanning membrane glycoprotein present on the surface of B cells. This gene belongs to the sialic acid-binding Ig-type lectin (Siglec) family. CD22 is mapped to human chromosome 19q13.

Immunogen

The antiserum was produced against synthesized peptide derived from human BL-CAM around the phosphorylation site of Tyr807.

Immunogen Range: 776-825

Biochem./physiol. Wirkung

CD22 (cluster of differentiation 22) helps to maintain B-cell homeostasis. This molecule act as an inhibitory coreceptor of the BCR (B cell receptor). CD22 is considered as a response regulator to control several aspects of B cell functions. Deficiency in CD22 or its pathways may contribute to autoimmunity.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable