SAB4504450

Anti-phospho-SAPK/JNK (pTyr¹⁸⁵) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-JNK, Anti-JNK-46, Anti-JNK1, Anti-JNK1A2, Anti-JNK21B1/2, Anti-PRKM8, Anti-SAPK1, Anti-SAPK1c
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 48 kDa
• Speziesreaktivität: mouse, rat, human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P45983; P45984; P53779
• UniProt-Hinterlegungsnummer: P45983
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr185)
• Angaben zum Gen: human ... MAPK10(5602) , MAPK8(5599) , MAPK9(5601)

Beschreibung

Allgemeine Beschreibung

MAPK9 (mitogen-activated protein kinase 9)/JNK2 (C-Jun N-terminal kinase 2)/ stress-activated protein kinase 2 (SAPK2) spans around 58494bp. The JNK2 gene is located on human chromosome 5q35. It has 17 introns.

Immunogen

The antiserum was produced against synthesized peptide derived from human SAPK/JNK around the phosphorylation site of Tyr185.

Immunogen Range: 151-200

Biochem./physiol. Wirkung

Stress-activated protein kinase 2 (SAPK2) participates in proliferation, differentiation, apoptosis, migration, transcriptional regulation and development. It controls the cellular acidic/lysosomal cellular compartment. JNK2 plays an important role in mediating stress-induced apoptosis and modulating gene expression.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable