SAB4503874

Anti-phospho-GR (pSer²²⁶) antibody produced in rabbit

affinity isolated antibody

• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 85 kDa
• Speziesreaktivität: mouse, rat, human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:5000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P04150
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer226)
• Angaben zum Gen: human ... GCR(2908)

Beschreibung

Allgemeine Beschreibung

Glucocorticoid receptor (GR) gene/NR3C1 (nuclear receptor subfamily 3 group C member 1) is located on human chromosome 5q31. It belongs to the steroid receptor superfamily that has ligand-activated nuclear transcription factors.

Immunogen

The antiserum was produced against synthesized peptide derived from human GR around the phosphorylation site of Ser226.

Immunogen Range: 201-250

Biochem./physiol. Wirkung

The glucocorticoid receptor (GR) gene/(NR3C1) is associated with asthma. It is required for glucose homeostasis and has been associated with hyperinsulinemia and increased fat deposition. GR also regulates cell differentiation, nervous and immune system functions.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable