SAB4503872

Anti-phospho-Fyn (pTyr⁵³⁰) antibody produced in rabbit

affinity isolated antibody

• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 60 kDa
• Speziesreaktivität: rat, human, mouse
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:1000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P06241
• UniProt-Hinterlegungsnummer: P06241
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr530)
• Angaben zum Gen: human ... FYN(2534)

Beschreibung

Allgemeine Beschreibung

Tyrosine-protein kinase FYN is a neuronally enriched cytoplasmic protein. It is encoded by the genes mapped to human chromosome 6q21. FYN protein belongs to the proto-oncogene tyrosine-protein kinase, Src family.

Immunogen

The antiserum was produced against synthesized peptide derived from human Fyn around the phosphorylation site of Tyr530.

Immunogen Range: 488-537

Anwendung

Anti-phospho-Fyn (pTyr530) antibody produced in rabbit has been used in immunoprecipitation and immunoblotting.

Biochem./physiol. Wirkung

Tyrosine-protein kinase FYN and phospho-FYN act as signaling systems for spatial memory. Phospho-FYN plays a vital role in the regulation of oligodendrocyte myelination and neurofilament phosphorylation. FYN aids in the development and activation of T cells in various physiological conditions. Overexpression of the FYN gene has been observed in various types of cancer.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable