SAB4503399

Anti-LAT3 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): L-type amino acid transporter 3, Prostate cancer overexpressed gene 1 protein, SLC43A1, Solute carrier family 43 member 1
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 61 kDa
• Speziesreaktivität: human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:20000; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: O75387
• UniProt-Hinterlegungsnummer: O75387
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... SLC43A1(8501)

Beschreibung

Allgemeine Beschreibung

Anti-LAT3 Antibody detects endogenous levels of total LAT3 protein.

LAT3/SLC43A1 (solute carrier family 43 member 1), a Na⁺-independent neutral L-amino acid transporter, is mapped to human chromosome 11q12.1. It is expressed in liver, skeletal muscle and pancreas.

Immunogen

The antiserum was produced against synthesized peptide derived from human LAT3.

Immunogen Range: 231-280

Biochem./physiol. Wirkung

LAT3/SLC43A1 (solute carrier family 43 member 1) is essential for the growth and activities of podocytes. In prostate cancer cell lines, silencing the expression of LAT3 stops the initiation of mTORC1 (mammalian target of rapamycin complex 1) pathway activation, cell growth and cell cycle both in vitro and in vivo.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable