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Key Documents

SAB4503373

Sigma-Aldrich

Anti-TEAD2 antibody produced in rabbit

affinity isolated antibody

Synonym(e):

TEA domain family member 2, TEAD-2

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 49 kDa

Speziesreaktivität

human, mouse

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100

NCBI-Hinterlegungsnummer

Q15562

UniProt-Hinterlegungsnummer

Q15562

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... TEAD2(8463)

Verwandte Kategorien

Allgemeine Beschreibung

TEA domain transcription factor 2 (TEAD2) belongs to the TEAD family. TEAD2 gene is located on human chromosome 19q13.3 Anti-TEAD2 antibody detects endogenous levels of total TEAD2 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human TEAD2.

Immunogen Range: 71-120

Anwendung

Anti-TEAD2 antibody produced in rabbit has been used in western blotting.

Biochem./physiol. Wirkung

TEA domain transcription factor 2 (TEAD2) plays a regulatory role in cell stemness. It modulates the expression of several genes. TEAD2 participates in the maintenance of cell survival. It is essential during neural development. TEAD2 might be a new therapeutic target and a predictive indicator of hepatocellular carcinoma (HCC).

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis.
P Jacquemin et al.
Genomics, 55(1), 127-129 (1999-01-16)
Jong Seok Joo et al.
Oncology reports, 43(6), 1785-1796 (2020-04-24)
TEA Domain Transcription Factors (TEADs) are important in development and serve essential roles in tumorigenesis; however, the role of TEAD2 expression in hepatocellular carcinoma (HCC) has not been widely examined. The present study was conducted to investigate the expression status
Kotaro J Kaneko et al.
Genesis (New York, N.Y. : 2000), 45(9), 577-587 (2007-09-18)
TEAD2, one of the first transcription factors expressed at the beginning of mammalian development, appears to be required during neural development. For example, Tead2 expression is greatest in the dorsal neural crest where it appears to regulate expression of Pax3
Paula González-Alonso et al.
Cancers, 12(5) (2020-05-06)
Trastuzumab is the first-line targeted therapeutic drug for HER2-positive breast cancer, leading to improved overall survival. However, acquired resistance inevitably occurs. We aimed to identify, quantify, and assess the mechanisms of acquired resistance to trastuzumab. We established an acquired trastuzumab-resistant

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