SAB4502616

Anti-NF-κB p65 (Acetyl-Lys³¹⁰) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): NFKB3, RELA, TF65, nuclear factor NF-κ-B p65 subunit, p65
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 60 kDa
• Speziesreaktivität: mouse, human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:40000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: Q04206
• UniProt-Hinterlegungsnummer: Q04206
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: acetylation (Lys310)
• Angaben zum Gen: human ... RELA(5970)

Beschreibung

Allgemeine Beschreibung

Anti-NF-κB p65 (Acetyl-Lys310) Antibody detects endogenous levels of total NF-κB p65 (Acetyl-Lys310) protein.
RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A) codes for the important constituent of the NF-κB (nuclear factor κ-B) complex. It is located on human chromosome 11q13.1. It is also called as nuclear factor κB subunit 3 (NFKB3).

Immunogen

The antiserum was produced against synthesized peptide derived from human NF-kappaB p65 around the acetylated site of Lys310.

Immunogen Range: 275-324

Anwendung

Anti-NF-κB p65 (Acetyl-Lys310) antibody has been used in western blotting.

Biochem./physiol. Wirkung

RELA (v-rel avian reticuloendotheliosis viral oncogene homolog A) participates in nuclear factor κ-B (NFKB) signaling pathway. It also controls inflammation. Alterations in the gene results in schizophrenia and startle reactions.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable