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Merck

SAB4502489

Sigma-Aldrich

Anti-Parathyroid Hormone antibody produced in rabbit

affinity isolated antibody

Synonym(e):

PTH/PTHr receptor, PTH/PTHrP type I receptor, PTHR1, Parathyroid hormone/parathyroid hormone-related peptide receptor precursor

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 12 kDa

Speziesreaktivität

human

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:10000
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... PTH(5741)

Allgemeine Beschreibung

Anti-Parathyroid Hormone antibody detects endogenous levels of total parathyroid hormone protein.
The PTH (parathyroid hormone) gene is mapped to human chromosome 11p15.3.

Immunogen

The antiserum was produced against synthesized peptide derived from human Parathyroid Hormone.

Immunogen Range: 51-100

Biochem./physiol. Wirkung

PTH (parathyroid hormone) significantly maintains calcium and phosphate homeostasis. The function of PTH is brought about by PTH receptor, a G protein-coupled receptor. Upregulation of PTH is observed in hyperparathyroidism, which leads to hypertension, bone and cardiovascular disease. PTH is also known to improve fracture healing.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Parathyroid pathology: hyperparathyroidism and parathyroid tumors.
Carlson D
Archives of Pathology & Laboratory Medicine, 134(11), 1639-1644 (2010)
Effects of parathyroid hormone 1-34 on osteogenic and chondrogenic differentiation of human fracture haematoma-derived cells in vitro.
Dogaki Y
Journal of Tissue Engineering and Regenerative Medicine, 10(10), E365-E371 (2016)
Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport.
Sneddon WB
The Journal of Biological Chemistry, 291(36), 18632-18642 (2016)
Genetic Variants Associated with Circulating Parathyroid Hormone.
Robinson-Cohen C
Journal of the American Society of Nephrology, 28(5), 1553-1565 (2017)
N Demirkan et al.
International journal of immunopathology and pharmacology, 27(2), 253-260 (2014-07-10)
The aim of this study is to investigate the histopathological findings of drill hole healing and interactions of parathyroid hormone (PTH), β-catenin and transcription factor-4 (TCF7L2/Tcf-4) after local application of recombinant human bone morphogenic protein-2 (rhBMP-2). Sprague Dawley rats were

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