SAB4501909

Anti-MAT1 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): AMS1, AdoMet synthetase, MAT-I/III, MATA1
• MDL-Nummer: MFCD00211613
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 35 kDa
• Speziesreaktivität: rat, mouse, human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:20000; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P51948
• UniProt-Hinterlegungsnummer: P51948
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... MNAT1(4331)

Beschreibung

Allgemeine Beschreibung

Anti-MAT1 Antibody detects endogenous levels of total MAT1 protein. CDK activating kinase assembly factor MNAT1 or MAT1 enzyme is encoded by the MNAT1 gene in humans and is localized to chromosome 14q23. The protein is part of the cyclin-dependent kinase-activating kinase complex.

Immunogen

The antiserum was produced against synthesized peptide derived from human MAT1.

Immunogen Range: 91-140

Biochem./physiol. Wirkung

CDK activating kinase assembly factor MNAT1 or MAT1 is functionally associated with the general transcription/DNA repair factor TFIIH. It is an assembly factor that targets subunits of both cyclin-dependent kinase-activating kinase (CAK) and TFIIH kinase. MAT1 regulates cell cycle and transcription. This protein associates with cyclin H and cyclin-dependent kinase 7 (CDK7) and forms the CDK-activating kinase (CAK) complex. The complex activates several cyclin-associated kinases, regulates cell cycle progression and activates RNA polymerase II-mediated transcription.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable