SAB4501900

Anti-MMP-13 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Collagenase 3, MMP-13, MMP13, Matrix metalloproteinase-13
• MDL-Nummer: MFCD03455405
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 53 kDa
• Speziesreaktivität: human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:40000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P45452
• UniProt-Hinterlegungsnummer: P45452
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... MMP13(4322)

Beschreibung

Allgemeine Beschreibung

Anti-MMP-13 Antibody detects endogenous levels of total MMP-13 protein.

Matrix metalloproteinases (MMPs) are a class of extra-cellular and membrane-bound proteases. MMP13 (matrix metallopeptidase 13) is mapped to human chromosome 11q14.3–23.2.

Immunogen

The antiserum was produced against synthesized peptide derived from human MMP-13.

Immunogen Range: 10-59

Biochem./physiol. Wirkung

MMP13 (matrix metallopeptidase 13) participates in tissue remodeling, inflammation, cytokine secretion and activation. It also plays an important role in acute lung injury, viral infections and chronic obstructive pulmonary disease. Mutation in MMP13 results in spondyloepimetaphyseal dysplasia, missouri type (SEMDMO).

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable