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Merck

SAB4501467

Sigma-Aldrich

Anti-APLP2 antibody produced in rabbit

affinity isolated antibody

Synonym(e):

APLP2, APP2, APPH, Amyloid protein homolog, Amyloid-like protein 2 precursor

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 86 kDa

Speziesreaktivität

rat, human, mouse

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:40000
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... APLP2(334)

Allgemeine Beschreibung

Anti-APLP2 Antibody detects endogenous levels of total APLP2 protein.
APLP2 (amyloid precursor-like protein 2) belongs to the amyloid precursor protein family. It is mapped to human chromosome 11q24.

Immunogen

The antiserum was produced against synthesized peptide derived from human APLP2.

Immunogen Range: 241-290

Biochem./physiol. Wirkung

Amyloid precursor-like protein 2 (APLP2) aids in the proliferation of pancreatic cancer growth and metastasis. It controls the expression of cell surface proteins. APLP2 plays an important role in chromosome replication and segregation.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Mechanism for amyloid precursor-like protein 2 enhancement of major histocompatibility complex class I molecule degradation.
Tuli A, et al.
The Journal of Biological Chemistry, 284(49), 34296-34307 (2009)
Identification and expression of the first nonmammalian amyloid-beta precursor-like protein APLP2 in the amphibian Xenopus laevis.
Collin RW, et al.
European Journal of Biochemistry, 271(10), 1906-1912 (2004)
Poomy Pandey et al.
Oncotarget, 6(4), 2064-2075 (2015-01-13)
Amyloid precursor-like protein 2 (APLP2) is aberrantly expressed in pancreatic cancer. Here we showed that APLP2 is increased in pancreatic cancer metastases, particularly in metastatic lesions found in the diaphragm and intestine. Examination of matched human primary tumor-liver metastasis pairs

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