Direkt zum Inhalt
Merck
Alle Fotos(3)

Key Documents

SAB4500248

Sigma-Aldrich

Anti-DJ-1 antibody produced in rabbit

affinity isolated antibody

Synonym(e):

Oncogene DJ1, PARK7, Parkinson disease protein 7, Protein DJ-1

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(3)

About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 19 kDa

Speziesreaktivität

mouse, human

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

Q99497

UniProt-Hinterlegungsnummer

Q99497

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... PARK7(11315)

Allgemeine Beschreibung

Anti-DJ-1 Antibody detects endogenous levels of total DJ-1 protein.
DJ-1 (protein deglycase)/PARK7 (parkinsonism associated deglycase) is an oncogene, made of 189 amino acids. It is present in several human tissues and is located on chromosome 1p36.

Immunogen

The antiserum was produced against synthesized peptide derived from human DJ-1.

Immunogen Range: 21-70

Anwendung

Anti-DJ-1 antibody has been used in western blotting.

Biochem./physiol. Wirkung

In lung cancer patients, DJ-1 (protein deglycase) acts as a biomarker for the initial prognosis. It also acts as a serum biomarker for identifying high-risk endometrial cancer.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sie haben nicht das passende Produkt gefunden?  

Probieren Sie unser Produkt-Auswahlhilfe. aus.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

DJ-1 is a reliable serum biomarker for discriminating high-risk endometrial cancer
Di Cello A, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(6) (2017)
DJ-1 as a potential biomarker for the early diagnosis in lung cancer patients
Han B, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(6) (2017)
Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36
van Duijn CM, et al.
American Journal of Human Genetics, 69(3), 629-634 (2001)
Kuldip D Dave et al.
Neurobiology of disease, 70, 190-203 (2014-06-28)
Recessively inherited loss-of-function mutations in the PTEN-induced putative kinase 1(Pink1), DJ-1 (Park7) and Parkin (Park2) genes are linked to familial cases of early-onset Parkinson's disease (PD). As part of its strategy to provide more tools for the research community, The
Min Sik Choi et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(45), 15123-15131 (2014-11-08)
Emerging evidence suggests that oxidative/nitrosative stress, as occurs during aging, contributes to the pathogenesis of Parkinson's disease (PD). In contrast, detoxification of reactive oxygen species and reactive nitrogen species can protect neurons. DJ-1 has been identified as one of several

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.