SAB4301399

Anti-phospho-DRP1 (pSer⁶³⁷) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): DLP1, DNM1L, DRP1, DVLP, Dymple
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 82 kDa
• Speziesreaktivität: human
• Konzentration: 1.0 mg/mL
• Methode(n): western blot: 1:500-1:1000 (Cell Lysate)
• Isotyp: IgG
• Hinterlegungsnummer: NP_036192.2.
• UniProt-Hinterlegungsnummer: O00429
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer637)
• Angaben zum Gen: human ... DNM1L(10059)

Beschreibung

Allgemeine Beschreibung

Dynamin related protein 1 (DRP1) is a dynamin-related guanosine triphosphatase. The gene is located on human chromosome 12p11.21. DRP1 is a cytosolic protein, which is also present on the outer mitochondrial membrane.

Spezifität

The antibody detects endogenous levels of DRP1 only when phosphorylated at serine 637.

Immunogen

Peptide sequence around phosphorylation site of Serine637(K-L-S(p)-A-R) derived from Human DRP1.

Anwendung

Anti-phospho-DRP1 (pSer⁶³⁷) antibody produced in rabbit has been used in immunoblotting and western blotting.

Biochem./physiol. Wirkung

Dynamin related protein 1 (DRP1) is an important regulator of mitochondrial fission and peroxisomal division. It regulates proper mitochondrial function, apoptosis and necrosis. Mutations in this gene is associated with Alzheimer′s disease.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable