SAB4300047

Anti-phospho-PTK2 (pTyr⁸⁶¹) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-FADK antibody produced in rabbit, Anti-FAK antibody produced in rabbit, Anti-FAK1 antibody produced in rabbit, Anti-PTK2 protein tyrosine kinase 2 antibody produced in rabbit, Anti-pp125FAK antibody produced in rabbit
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~125 kDa
• Speziesreaktivität: human
• Konzentration: 1 mg/mL
• Methode(n): western blot: 1:500-1:1000
• Isotyp: IgG
• Immunogene Sequenz: (H-I-YP-Q-P)
• NCBI-Hinterlegungsnummer: NP_005598.3
• UniProt-Hinterlegungsnummer: Q05397
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr861)
• Angaben zum Gen: human ... PTK2(5747)

Beschreibung

Immunogen

Peptide sequence around phosphorylation site of tyrosine 861 (H-I-Y(p)-Q-P), according to the protein PTK2.

Leistungsmerkmale und Vorteile

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Zielbeschreibung

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable