SAB4200197

Anti-Periostin antibody,Mouse monoclonal

clone 47, purified from hybridoma cell culture

• Synonym(e): Periostin Antibody, Periostin Antibody - Monoclonal Anti-Periostin antibody produced in mouse, Anti-OSF2, Anti-Osteoblast specific factor 2, Anti-PDLPOSTN, Anti-POSTN
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Konjugat: unconjugated
• Antikörperform: purified from hybridoma cell culture
• Antikörper-Produkttyp: primary antibodies
• Klon: 47, monoclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen ~88 kDa
• Speziesreaktivität: human
• Konzentration: ~1.0 mg/mL
• Methode(n): western blot: 2-4 μg/mL using whole extracts of HEK-293T cells over expressing human Periostin
• Isotyp: IgG1
• UniProt-Hinterlegungsnummer: Q15063
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... POSTN(10631)

Beschreibung

Allgemeine Beschreibung

Periostin (POSTN) is also known as osteoblast-specific factor-2. It is a 90 kDa protein expressed in the extracellular matrix and bones. POSTN is an adhesive glycoprotein. The gene encoding this protein is localized on human chromosome 13q13.3.

Immunogen

human Periostin recombinant protein. The human protein shares 87% homology with the mouse protein.

Anwendung

Monoclonal Anti-Periostin antibody produced in mouse has been used to develop a periostin imaging PET probe.

Biochem./physiol. Wirkung

Periostin (POSTN) has a role in the differentiation and cell adhesion of osteogenic cells. It functions as a biomarker of T-helper cells type 2-mediated inflammatory diseases. The protein has been associated with various cancers. POSTN is involved in epithelial-mesenchymal transition and extracellular matrix degradation.

Physikalische Form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable