SAB1406356

Anti-PYCR1 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

• Synonym(e): P5C, P5CR, PIG45, PP222, PYCR
• UNSPSC-Code: 12352203
• NACRES: NA.41
• Konjugat: unconjugated
• application: IF; WB
• Klon: polyclonal
• Speziesreaktivität: human
• citations: 5
• Methode(n): indirect immunofluorescence: suitable; western blot: 1 μg/mL

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen ~33.4 kDa
• Speziesreaktivität: human
• Methode(n): indirect immunofluorescence: suitable; western blot: 1 μg/mL
• NCBI-Hinterlegungsnummer: NM_006907.2
• UniProt-Hinterlegungsnummer: P32322
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... PYCR1(5831)

Beschreibung

Allgemeine Beschreibung

Pyrroline-5-carboxylate reductase 1 (PYCR1) is a housekeeping gene.The gene is located on human chromosome 17q25.3.

Immunogen

PYCR1 (NP_008838.2, 1 a.a. ~ 319 a.a) full-length human protein.

Sequence
MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD

Biochem./physiol. Wirkung

Pyrroline-5-carboxylate reductase 1 (PYCR1) acts as a prognostic biomarker for breast cancer.Mutations in this gene affects mitochondrial function and is associated with connective tissue disorder cutis laxa.It helps in cell metabolism.This protein catalyses the conversion of 1-piperideine-6-carboxylate (P6C) into pipecolic acid.

Physikalische Form

Solution in phosphate buffered saline, pH 7.4

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable