SAB1306674

ANTI-ALDOLASE (ALDOA)(N-TERMINAL) antibody produced in rabbit

purified immunoglobulin, buffered aqueous solution

• Synonym(e): ALDA, ALDOA, Fructose-bisphosphate aldolase A, Lung cancer antigen NY-LU-1, Muscle-type aldolase
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 39420 Da
• Speziesreaktivität: human
• Methode(n): immunofluorescence: 1:10-1:50; immunohistochemistry: 1:10-1:50; western blot: 1:1000
• NCBI-Hinterlegungsnummer: NP_000025.1
• UniProt-Hinterlegungsnummer: P04075
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... ALDOA(226)

Beschreibung

Allgemeine Beschreibung

Aldolase A, fructose-bisphosphate (ALDOA) is a ubiquitous glycolytic enzyme expressed in developing embryo and in adult muscle. It is involved in a wide range of cellular functions such as maintenance of striated muscle contraction, cell shape and mobility, actin filament organization and ATP biosynthetic process.

Anwendung

ANTI-ALDOLASE (ALDOA)(N-TERMINAL) antibody produced in rabbit is suitable for immunofluorescence (1:10-1:50), immunohistochemistry (1:10-1:50), and western blot (1:1000) applications.

Biochem./physiol. Wirkung

In glycolysis, ALDOA catalyzes the reversible reaction of fructose-1,6-bisphosphate to glyceraldehydes-3-phosphate and dihydroxyacetone phosphate. High expression level of ALDOA is reported in various forms of malignant cancers, including human lung squamous, renal cell and hepatocellular carcinomas. ALDOA deficiency causes myopathy and hemolytic anemia.

Physikalische Form

Supplied in PBS with 0.09% (W/V) sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable