SAB1300666

Anti-SULT1B1 (C-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Synonym(e): Anti-1B, Anti-Cytosolic, Anti-Member 1, Anti-Sulfotransferase family, Sulfotransferase 1B2
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: IgG fraction of antiserum
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Methode(n): indirect ELISA: 1:1000; western blot: 1:100-1:500
• NCBI-Hinterlegungsnummer: NP_055280
• UniProt-Hinterlegungsnummer: O43704
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... SULT1B1(27284)

Beschreibung

Allgemeine Beschreibung

Sulfotransferases such as SULT1B1 catalyze the biotransformation of a large number of endogenous compounds such as neurotransmitters, steroids, bile acids, and thyroid hormones, as well as drugs and xenobiotics. Fujita et al. (1997) demonstrated that recombinant rat and human SULT1B1, expressed in E. coli, catalyzed sulfation of p-nitrophenol, 3,3-prime,5-triiodothyronine (T3), and dopamine, but not of beta-estradiol and dehydroepiandrosterone. SULT1B1 showed higher affinities for formation of T3 sulfate than did the phenol sulfotransferases ST1A3 (SULT1A1) or ST1A5. Wang et al. (1998) found that bacterially-expressed SULT1B1 sulfated small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3-prime-diiodothyronine, triiodothyronine, reverse triiodothyronine, and thyroxine. No activity was detected against several sterols or dopamine.

Immunogen

SULT1B1 (NP_055280, 268-306)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SULT1B1.

Physikalische Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable