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S6635

Sigma-Aldrich

Span® 20

greener alternative

Synonym(e):

Sorbitan-monolaurat

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About This Item

CAS-Nummer:
1338-39-2
EG-Nummer:
215-663-3
MDL-Nummer:
MFCD00005365
UNSPSC-Code:
12161900
PubChem Substanz-ID:
24899716
NACRES:
NA.25

Beschreibung

non-ionic

Mol-Gew.

346.47 g/mol

Grünere Alternativprodukt-Eigenschaften

Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Konzentration

≥44% (GC)

Grünere Alternativprodukt-Kategorie

, Aligned

SMILES String

CCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O

InChI

1S/C18H34O6/c1-2-3-4-5-6-7-8-9-10-11-16(21)23-13-15(20)18-17(22)14(19)12-24-18/h14-15,17-20,22H,2-13H2,1H3/t14-,15?,17+,18+/m0/s1

InChIKey

LWZFANDGMFTDAV-WYDSMHRWSA-N

Verwandte Kategorien

Allgemeine Beschreibung

Span 20 is a co-surfactant.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is 100% bio-based non-ionic surfactant, thus aligns with "Use of Renewable Feedstocks" and belongs to "12 principles aligned" category of our greener alternatives.

Anwendung

Span 20 has been used in a study to assess enhanced solubility and oral bioavailability of itraconazole. It has also been used in a study to investigate the oxidation of unsaturated lipids in oil-in-water emulsions.

Sonstige Hinweise

Fatty acid composition: Lauric acid (C12:0) ≥ 44%; balance primarily myristic (C14:0), palmitic (C16:0) and linolenic (C18:3) acids.

Rechtliche Hinweise

Span is a registered trademark of Croda International PLC

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

>300.2 °F - closed cup

Flammpunkt (°C)

> 149 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Claire Berton et al.
Journal of colloid and interface science, 377(1), 244-250 (2012-04-25)
The development of lipid oxidation in oil-in-water (O/W) emulsions is widely influenced by the properties of the interfacial layer, which separates the oil and water phases. In this work, the effect of the structure of the interface on the oxidative
Sinead Hickey et al.
International journal of pharmaceutics, 388(1-2), 213-222 (2009-12-17)
High-resolution ultrasonic spectroscopy was applied to analyse a pseudo-ternary phase diagram for a mixture consisting of water/ethyl oleate/Tween 80 and Span 20 at 25 degrees C. The measured changes in the ultrasonic velocity and attenuation with concentration of water in
Pao-Chu Wu et al.
Drug development and industrial pharmacy, 36(12), 1398-1403 (2010-06-16)
Nicardipine hydrochloride has been used widely for the treatment of angina pectoris and hypertension. Because of its extensive first pass metabolism after oral administration, the transdermal administration of nicardipine microemulsions was developed in this study. Microemulsions consisted of isopropyl myristate
Gabriela Calderó et al.
Journal of colloid and interface science, 353(2), 406-411 (2010-10-26)
Formation of polymeric O/W nano-emulsions has been studied in the water/polyoxyethylene 4 sorbitan monolaurate/ethylcellulose solution system by the phase inversion composition (PIC) method. These nano-emulsions were used for the preparation of nanoparticles by solvent evaporation. Composition variables such as O/S
Orapan Paecharoenchai et al.
Journal of drug targeting, 20(9), 783-792 (2012-08-31)
Non-ionic surfactant-based vesicles (niosomes) composed of non-ionic surfactants (i.e., Tween and Span) and cholesterol were formulated, and their turbidity and particle size assayed. The most appropriate niosomes formulation was mixed with novel synthesized spermine-based cationic lipids to prepare cationic niosomes
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