S3147

5-Sulfosalicylsäure Dihydrat

suitable for electrophoresis, ≥99%

• Synonym(e): 2-Hydroxy-5-Sulfobenzoesäure
• Lineare Formel: HO₃SC₆H₃-2-(OH)CO₂H·2H₂O
• CAS-Nummer: 5965-83-3
• Molekulargewicht: 254.21
• Beilstein: 650741
• EG-Nummer: 202-555-6
• MDL-Nummer: MFCD00149540
• UNSPSC-Code: 41105319
• PubChem Substanz-ID: 24899547
• NACRES: NB.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥99%
• Form: powder or crystals
• Methode(n): electrophoresis: suitable
• Verunreinigungen: ≤0.02% Insoluble matter; ≤0.05% Salicylic Acid
• mp (Schmelzpunkt): 105-110 °C (lit.)
• Löslichkeit: water: soluble 100 mg/mL, clear, colorless
• Anionenspuren: chloride (Cl^-): ≤0.001%; sulfate (SO₄^2-): ≤0.035%
• Kationenspuren: Fe: ≤0.001%; heavy metals (as Pb): ≤0.002%
• SMILES String: [H]O[H].[H]O[H].OC(=O)c1cc(ccc1O)S(O)(=O)=O
• InChI: 1S/C7H6O6S.2H2O/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10;;/h1-3,8H,(H,9,10)(H,11,12,13);2*1H2
• InChIKey: BHDKTFQBRFWJKR-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

5-Sulfosalicylic acid is a strong acid capable of protonating water. It forms a new theophylline complex, which was investigated by X-ray photoelectron spectroscopy (XPS). It forms 1:1 proton-transfer compounds with the ortho-substituted monocyclic heteroaromatic Lewis bases. Their crystal structures have been studied.

Anwendung

5-Sulfosalicylic acid (3.5%) in 12% trichloroacetic acid is commonly used as a fixing solution for proteins in agarose and polyacrylamide gels.

5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC. It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([μ]-5-sulfonatosalicylato)tricopper(II)] trihydrate].

Hinweis zur Analyse

Tested for use in fixing solutions for PAGE, SDS-PAGE and IEF.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Gefahreneinstufungen: Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves