S1701

Anti-SDCBP antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-MDA-9, Anti-Melanoma differentiation associated protein-9, Anti-Pro-TGF-alpha cytoplasmic domain-interacting protein 18, Anti-Scaffold protein Pbp1, Anti-ST1, Anti-SYCL, Anti-Syndecan binding protein (syntenin), Anti-Syntenin, Anti-TACIP18
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 200
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Form: buffered aqueous solution
• Mol-Gew.: antigen ~30 kDa
• Speziesreaktivität: mouse, human, rat
• Konzentration: ~1.0 mg/mL
• Methode(n): immunoprecipitation (IP): 10-20 μg using lysates of human HeLa cells; indirect immunofluorescence: 2-5 μg/mL using human HeLa cells; western blot: 2-4 μg/mL using whole extract of human HEK-293T cells, rat NRK cells, or mouse Neuro-2a cells
• UniProt-Hinterlegungsnummer: O00560
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... SDCBP(6386)

Beschreibung

Allgemeine Beschreibung

Syndecan binding protein (SDCBP), also known as syntenin and melanoma differentiation associated gene-9 (mda-9), was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. SDCBP contains tandemly repeated PDZ domains that binds the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. SDCBP is primarily localized to membrane associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus.

Anwendung

Anti-SDCBP antibody produced in rabbit has been used in:

• enzyme linked immuno sorbent assay (ELISA)
• immunoblotting
• immunocytochemistry

Biochem./physiol. Wirkung

Syndecan binding protein (SDCBP) regulates cytoskeletal-membrane organization, cell adhesion, protein trafficking and the activation of transcription factors. SDCBP promotes metastasis in human melanoma cells by activating c-Src.

Physikalische Form

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable