R6527

Reboxetin Hydrat

>96% (HPLC), solid

• Synonym(e): (2R)-rel-2-[(R)-(2-Ethoxyphenoxy)-phenylmethyl]-morpholin, Edronax, Vestra
• Empirische Formel (Hill-System): C₁₉H₂₃NO₃ · CH₃SO₃H · xH₂O
• CAS-Nummer: 98769-84-7
• Molekulargewicht: 409.50 (anhydrous basis)
• MDL-Nummer: MFCD11046031
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24724592
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: >96% (HPLC)
• Form: solid
• Lagerbedingungen: desiccated
• Farbe: white to tan
• Löslichkeit: H₂O: >5 mg/mL at ≤60 °C
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• SMILES String: O.CS(O)(=O)=O.CCOc1ccccc1O[C@@H]([C@H]2CNCCO2)c3ccccc3
• InChI: 1S/C19H23NO3.CH4O3S.H2O/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18;1-5(2,3)4;/h3-11,18-20H,2,12-14H2,1H3;1H3,(H,2,3,4);1H2/t18-,19-;;/m1../s1
• InChIKey: SZPHEVAYLIVGRC-BAMQSBMESA-N

Beschreibung

Anwendung

Reboxetine mesylate hydrate has been used as a selective norepinephrine transport blocker:

• to study its effects on the surge of dopamine in the cortex of mice brain
• to study its anti-immobility effects on the behavior of mice
• to analyze its effects on the probabilistic reversal learning task in rodents

Biochem./physiol. Wirkung

Selektiver Noradrenalin-Aufnahme-Inhibitor

Reboxetine exhibits anti-depressant activity.

Leistungsmerkmale und Vorteile

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)