R5155

Rocuronium -bromid

≥97% (perchloric acid titration)

• Synonym(e): (+)-Rocuronium bromide
• Empirische Formel (Hill-System): C₃₂H₅₃BrN₂O₄
• CAS-Nummer: 119302-91-9
• Molekulargewicht: 609.68
• MDL-Nummer: MFCD00867768
• UNSPSC-Code: 51152000
• PubChem Substanz-ID: 329824032
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥97% (perchloric acid titration)
• Form: powder
• Funktionelle Gruppe: ester
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: [Br-].CC(=O)O[C@H]1[C@H](C[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@H](C[C@]4(C)[C@H]3CC[C@]12C)N5CCOCC5)[N+]6(CCCC6)CC=C
• InChI: 1S/C32H53N2O4.BrH/c1-5-14-34(15-6-7-16-34)28-20-26-24-9-8-23-19-29(36)27(33-12-17-37-18-13-33)21-32(23,4)25(24)10-11-31(26,3)30(28)38-22(2)35;/h5,23-30,36H,1,6-21H2,2-4H3;1H/q+1;/p-1/t23-,24+,25-,26-,27-,28-,29-,30-,31-,32-;/m0./s1
• InChIKey: OYTJKRAYGYRUJK-FMCCZJBLSA-M
• Angaben zum Gen: human ... CHRNA1(1134) , CHRNB1(1140) , CHRND(1144) , CHRNE(1145) , CHRNG(1146)

Beschreibung

Biochem./physiol. Wirkung

Rocuronium Bromide is a fumarate, non-depolarizing, neuromuscular blocking agent. It is rapid-acting, relaxes the skeletal muscle and decreases oxygen consumption during surgery. It competes with acetylcholine and bind to cholinergic receptors at neuromuscular junctions.

Aminosteroid; neuromuskulärer Blocker für Anästhesie

Angaben zur Herstellung

Rocuronium bromide yields clear, light yellow solution in water at 100 mg/ml.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301,H335
• P-Sätze: P261 - P264 - P271 - P301 + P310 - P304 + P340 + P312 - P403 + P233
• Gefahreneinstufungen: Acute Tox. 3 Oral - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)