PZ0151

PF-956980 hydrate

≥98% (HPLC)

• Synonym(e): {(3R,4R)-4-Methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-pyrrolidin-1-yl-methanone hydrate
• Empirische Formel (Hill-System): C₁₈H₂₆N₆O · xH₂O
• CAS-Nummer: 1262750-62-8
• Molekulargewicht: 342.44 (anhydrous basis)
• MDL-Nummer: MFCD18452852
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 329823736
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D +33 to +40°, c = 0.5 in methanol
• Farbe: white to off-white
• Löslichkeit: DMSO: ≥50 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: O.C[C@@H]1CCN(C[C@@H]1N(C)c2ncnc3[nH]ccc23)C(=O)N4CCCC4
• InChI: 1S/C18H26N6O.H2O/c1-13-6-10-24(18(25)23-8-3-4-9-23)11-15(13)22(2)17-14-5-7-19-16(14)20-12-21-17;/h5,7,12-13,15H,3-4,6,8-11H2,1-2H3,(H,19,20,21);1H2/t13-,15+;/m1./s1
• InChIKey: VZUKSTKLTSSYKP-PBCQUBLHSA-N

Beschreibung

Biochem./physiol. Wirkung

PF-956980 is a FGF1 receptor antagonist; PDGF receptor modulator; Flt3 tyrosine kinase modulator; and VEGF antagonist.

Leistungsmerkmale und Vorteile

This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301 + H311 + H331
• P-Sätze: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable