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P7857

Sigma-Aldrich

Anti-P2X1 Purinergic Receptor antibody produced in rabbit

affinity isolated antibody, lyophilized powder

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About This Item

MDL-Nummer:
MFCD02097115
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

200

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

lyophilized powder

Speziesreaktivität

rat, human

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot (chemiluminescent): 1:200

UniProt-Hinterlegungsnummer

P51575

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... P2RX1(5023)
mouse ... P2rx1(18436)
rat ... P2rx1(25505)

Verwandte Kategorien

Immunogen

synthetic peptide corresponding to amino acids 382-399 of rat P2X1 (with additional N-terminal cysteine and serine). The epitope is highly conserved in mouse and human.

Physikalische Form

Lyophilized at ~0.6 mg/ml from a solution of phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
SLCM3889
SLCL0434
SLBP2723
059K1235
117K1257

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C M Chan et al.
The American journal of physiology, 274(4 Pt 2), F799-F804 (1998-05-12)
P2 receptors have been identified in rat kidney by autoradiography, using the radioligand [3H] alpha, beta-methylene ATP, and by immunohistochemistry, using a polyclonal antibody to the P2X1 purinoceptor. They have been localized to the vascular smooth muscle of intrarenal arteries
Derek M Kendig et al.
American journal of physiology. Renal physiology, 310(9), F909-F922 (2016-01-30)
Type II diabetes is the most prevalent form of diabetes. One of the primary complications of diabetes that significantly affects quality of life is bladder dysfunction. Many studies on diabetic bladder dysfunction have been performed in models of type I
G P Owens et al.
Molecular and cellular biology, 11(8), 4177-4188 (1991-08-01)
Programmed cell death is an essential cellular process that occurs in epithelial turnover, neural development, and regulation of cell populations of the immune system. Thymocytes undergo programmed cell death in response to several inductive stimuli, including exposure to glucocorticoids or
S Valera et al.
Nature, 371(6497), 516-519 (1994-10-06)
Extracellular ATP exerts its effects through P2 purinoceptors: these are ligand-gated ion channels (P2x) or G-protein-coupled receptors (P2Y, P2U). ATP at P2x receptors mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic
L Vulchanova et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(15), 8063-8067 (1996-07-23)
Several P2X receptor subunits were recently cloned; of these, one was cloned from the rat vas deferens (P2X1) and another from pheochromocytoma (PC12) cells differentiated with nerve growth factor (P2X2). Peptides corresponding to the C-terminal portions of the predicted receptor
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