P1851

PIPES

BioPerformance Certified, suitable for cell culture

• Synonym(e): 1,4-Piperazindiethansulfonsäure, Piperazin-1,4-bis(2-ethansulfonsäure), Piperazin-N,N′-bis-(2-ethansulfonsäure)
• Empirische Formel (Hill-System): C₈H₁₈N₂O₆S₂
• CAS-Nummer: 5625-37-6
• Molekulargewicht: 302.37
• Beilstein: 817713
• EG-Nummer: 227-057-6
• MDL-Nummer: MFCD00006159
• UNSPSC-Code: 12161700
• PubChem Substanz-ID: 24898249
• NACRES: NA.25

Eigenschaften

• Qualität: BioPerformance Certified; for molecular biology
• Form: crystalline powder
• Methode(n): cell culture | mammalian: suitable
• Verunreinigungen: endotoxin and Total Aerobic Microbial Count, tested
• Nützlicher pH-Bereich: 6.1-7.5
• pKa (25 °C): 6.8
• mp (Schmelzpunkt): >300 °C (lit.)
• Löslichkeit: 1 M NaOH: 20 + 80 mL g, clear, colorless; soluble
• Anwendung(en): diagnostic assay manufacturing
• Fremdaktivität: DNAse, Exonuclease; NICKase, Endonuclease; RNAse; Protease, none detected
• SMILES String: OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O
• InChI: 1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
• InChIKey: IHPYMWDTONKSCO-UHFFFAOYSA-N

Beschreibung

Anwendung

• Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics.: The use of PIPES buffer in this study was integral to maintaining the stability of immunoglobulin G during differential scanning fluorimetry. This method is crucial for evaluating the stability of antibody-based therapeutics (Moggridge et al., 2017).

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)