P0393

Protein Kinase Inhibitor from porcine heart

1-3 inhibitor U/μg protein, lyophilized powder

• MDL-Nummer: MFCD00132115
• UNSPSC-Code: 12352202

Eigenschaften

• Biologische Quelle: Porcine heart
• Form: lyophilized powder
• Spezifische Aktivität: 1-3 inhibitor U/μg protein
• Zusammensetzung: Protein, ~50% biuret
• Lagertemp.: 2-8°C

Beschreibung

Biochem./physiol. Wirkung

These proteins bind to the catalytic subunit of cyclic-AMP dependent protein kinase, displacing the regulatory subunit and inhibiting phosphorylating activity. The cyclic-AMP binding capacity of the regulatory subunit is enhanced. Many other proteins exhibit this enhancement ability, too (Brostrom, C.O. and Kon, C., Anal. Biochem., 58, 459 [1974]).

Verpackung

Package size based on protein content.

Einheitendefinition

One unit will transfer 1.0 picomole (10^-12 mol) of phosphate from γ-³²P-ATP to hydrolyzed and partially dephosphorylated casein (Product No. C 4765) per min at pH 6.5 at 30 °C.

Physikalische Form

Supplied as lyophilized powder containing 30% glycerophosphate and 20% EDTA.

Angaben zur Herstellung

Fractionated essentially by procedure of Walsh, D.A., et al., J. Biol. Chem., 246, 1977 (1971).

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)