N8501

5-Nitro-1,10-Phenanthrolin

≥97%, crystalline

• Synonym(e): Nitro-ferroin
• Empirische Formel (Hill-System): C₁₂H₇N₃O₂
• CAS-Nummer: 4199-88-6
• Molekulargewicht: 225.20
• Beilstein: 196245
• EG-Nummer: 224-097-6
• MDL-Nummer: MFCD00004981
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 24897678
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 100
• Assay: ≥97%
• Form: crystalline
• Farbe: yellow to orange
• mp (Schmelzpunkt): 202-204 °C (lit.)
• Löslichkeit: ethanol: 50 mg/mL, clear to slightly hazy, yellow to orange
• SMILES String: [O-][N+](=O)c1cc2cccnc2c3ncccc13
• InChI: 1S/C12H7N3O2/c16-15(17)10-7-8-3-1-5-13-11(8)12-9(10)4-2-6-14-12/h1-7H
• InChIKey: PDDBTWXLNJNICS-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Platinum chelates of a variety of 5-substituted phenanthrolines, including this compound, were tested for cytotoxicity against L1210 murine leukemia cells. Though all tested compounds had very similar DNA-binding affinities, they exhibited a wide range of cytotoxicity.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves