N165

Naloxone benzoylhydrazone

solid

• Synonym(e): [(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazide benzoic acid
• Empirische Formel (Hill-System): C₂₆H₂₇N₃O₄
• CAS-Nummer: 119630-94-3
• Molekulargewicht: 445.51
• MDL-Nummer: MFCD05662358
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24278048
• NACRES: NA.77

Eigenschaften

• Form: solid
• Arzneimittelkontrolle: regulated under CDSA - not available from Sigma-Aldrich Canada
• Farbe: yellow
• Löslichkeit: DMSO: soluble; H₂O: soluble (with the addition of 0.1 N HCl); ethanol: soluble
• Lagertemp.: −20°C
• SMILES String: [H][C@@]12Oc3c(O)ccc4C[C@H]5N(CC[C@@]1(c34)[C@@]5(O)CC\C2=N/NC(=O)c6ccccc6)CC=C
• InChI: 1S/C26H27N3O4/c1-2-13-29-14-12-25-21-17-8-9-19(30)22(21)33-23(25)18(10-11-26(25,32)20(29)15-17)27-28-24(31)16-6-4-3-5-7-16/h2-9,20,23,30,32H,1,10-15H2,(H,28,31)/b27-18+/t20-,23+,25+,26-/m1/s1
• InChIKey: AKXCFAYOTIEFOH-XTNAHFASSA-N
• Angaben zum Gen: human ... OPRK1(4986) , OPRL1(4987) , OPRM1(4988)

Beschreibung

Biochem./physiol. Wirkung

Agonist for κ₃ opioid receptors; antagonist for ORL₁ and μ opioid receptors.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)