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Wichtige Dokumente
MAK069
MPO Fluorometric Activity Assay Kit
sufficient for 100 fluorometric tests
Synonym(e):
Myeoloperoxidase Fluorometric Activity Assay Kit
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About This Item
UNSPSC-Code:
12161503
Empfohlene Produkte
Verwendung
sufficient for 100 fluorometric tests
Nachweisverfahren
fluorometric
Relevante Krankheit(en)
cancer; cardiovascular diseases; hematological disorder
Lagertemp.
−20°C
Angaben zum Gen
human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)
Allgemeine Beschreibung
Myeloperoxidase (MPO) is a heme-containing enzyme that catalyzes the hydrogen peroxidase-mediated oxidation of halide ions to hypohalous acid. MPO is a lysosomal protein, highly expressed in neutrophils, that plays a role in the antimicrobial actions that occur as a result of neutrophil stimulation. The actions of MPO may also contribute to the initiation and pathogenesis of cardiovascular disease.
Anwendung
MPO Fluorometric Activity Assay Kit has been used to determine the activity of myeloperoxidase.
Eignung
Suitable for the measurement of myeloperoxidase (MPO) in biological samples such as tissue, cells, serum and white blood cells
Prinzip
The MPO Activity Flurometric Assay kit provides a simple and direct procedure for measuring MPO activity in a variety of samples. In this assay, MPO catalyzes the formation of hypochlorous acid with reacts with the substrate, aminophenyl fluorescein, to generate fluorescein) (λex = 485/λem = 525 nm). One unit of MPO is the amount of enzyme that will oxidize the MPO substrate to yield 1.0 μmole of fluorescein per minute at room temperature.
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Gefahreneinstufungen
Resp. Sens. 1
Lagerklassenschlüssel
10 - Combustible liquids
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