L3042

Levostin

≥99% (HPLC), solid

• Synonym(e): Levocabastin -hydrochlorid, Levophta, R50547, [3S-[1(cis),3α,4β]]-1-[4-cyano-4-(4-fluorphenyl)cyclohexyl]-3-methyl-4-phenyl-4-piperidincarbonsäure
• Empirische Formel (Hill-System): C₂₆H₂₉N₂O₂F·HCl
• CAS-Nummer: 79547-78-7
• Molekulargewicht: 456.98
• MDL-Nummer: MFCD07787408
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329817402

Eigenschaften

• Assay: ≥99% (HPLC)
• Form: solid
• Farbe: white
• Löslichkeit: DMSO: soluble ~10 mg/mL
• Ersteller: Johnson & Johnson
• SMILES String: Cl[H].C[C@@H]1CN(CC[C@]1(C(O)=O)c2ccccc2)[C@@H]3CC[C@@](CC3)(C#N)c4ccc(F)cc4
• InChI: 1S/C26H29FN2O2.ClH/c1-19-17-29(16-15-26(19,24(30)31)21-5-3-2-4-6-21)23-11-13-25(18-28,14-12-23)20-7-9-22(27)10-8-20;/h2-10,19,23H,11-17H2,1H3,(H,30,31);1H/t19-,23-,25-,26-;/m1./s1
• InChIKey: OICFWWJHIMKBCD-VALQNVSPSA-N
• Angaben zum Gen: human ... HRH1(3269)

Beschreibung

Biochem./physiol. Wirkung

Non-peptide histamine H₁ receptor antagonist; neurotensin NTS₂ receptor ligand.

Leistungsmerkmale und Vorteile

This compound is featured on the Neurotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves