L0669

Monoclonal Anti-Leukemia Inhibitory Factor antibody produced in mouse

clone 9824, purified immunoglobulin, lyophilized powder

• Synonym(e): Anti-CDF, Anti-Cholinergic differentiation factor, Anti-HILDA, Anti-LIF
• UNSPSC-Code: 51111800
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: 9824, monoclonal
• Form: lyophilized powder
• Speziesreaktivität: human
• Methode(n): capture ELISA: 2-4 μg/mL; immunohistochemistry: 25 μg/mL; neutralization: suitable; western blot: 1-2 μg/mL
• UniProt-Hinterlegungsnummer: P15018
• Lagertemp.: −20°C
• Angaben zum Gen: human ... LIF(3976)

Beschreibung

Immunogen

purified, E. coli-derived recombinant human leukemia inhibitory factor.

Biochem./physiol. Wirkung

Leukemia inhibitory factor (LIF) is a pleotrophic glycoprotein that belongs to the IL-6 family of cytokines. It is secreted by many cell types such as, fibroblasts, macrophages, T cells, monocytes, liver cells, osteoblasts and cells of endometrium. A variety of signal transduction pathways are triggered in response to LIF including ERK/MAPK, JAK1, PI3K, STAT3, Jun-c Fos and NF-κB. The various functions of LIF include proliferation of adult human T cells, maintenance of pluripotency of embryonic stem cells and inhibition of leukemic cell differentiation.

Physikalische Form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)