K3000

Kinetinribosid

proapoptotic anitproliferative plant growth regulator

• Synonym(e): 6-Furfurylaminopurine riboside, N⁶-(2-Furanyl­methyl)adenosine, N⁶-Furfuryladenosine
• Empirische Formel (Hill-System): C₁₅H₁₇N₅O₅
• CAS-Nummer: 4338-47-0
• Molekulargewicht: 347.33
• EG-Nummer: 224-389-3
• MDL-Nummer: MFCD00037987
• UNSPSC-Code: 12352207
• PubChem Substanz-ID: 24896224
• NACRES: NA.72

Eigenschaften

• Assay: ≥98% (HPLC); ≥98% (TLC)
• Form: powder
• Löslichkeit: acetic acid: 49.00-51.00 mg/mL, clear, colorless to yellow
• Lagertemp.: 2-8°C
• SMILES String: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccco4)ncnc23
• InChI: 1S/C15H17N5O5/c21-5-9-11(22)12(23)15(25-9)20-7-19-10-13(17-6-18-14(10)20)16-4-8-2-1-3-24-8/h1-3,6-7,9,11-12,15,21-23H,4-5H2,(H,16,17,18)/t9-,11-,12-,15-/m1/s1
• InChIKey: CAGLGYNQQSIUGX-SDBHATRESA-N
• Angaben zum Gen: rat ... Adora1(29290) , Adora2a(25369) , Adora3(25370)

Beschreibung

Allgemeine Beschreibung

Kinetin riboside is a ribosylated form of kinetin. It is a natural cytokinin plant hormone.

Anwendung

Kinetin riboside may be used:

• to study its cytotoxic effects on plant and animal tumor cells
• to investigate its apoptotic effects in both cancer and immortalized cells
• to elucidate its influence on human prostate cell epithelial-mesenchymal transition in vitro

Biochem./physiol. Wirkung

Kinetin riboside exhibits cytotoxic and antiproliferative activities. In addition, it also shows anticancer activity by inducing apoptosis in various types of cancers including myeloid leukemia cells, mouse melanoma B16F-10 cells, and plant tumor cells.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)