I0531
Interleukin-18 from rat
>97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)
About This Item
Empfohlene Produkte
Biologische Quelle
rat
Qualitätsniveau
Rekombinant
expressed in E. coli
Assay
>97% (SDS-PAGE)
Form
lyophilized powder
Wirksamkeit
10-60 ng/mL ED50
Mol-Gew.
predicted mol wt ~18.4 kDa
Verpackung
pkg of 25 μg
Verunreinigungen
endotoxin, tested
UniProt-Hinterlegungsnummer
Versandbedingung
dry ice
Lagertemp.
−20°C
Angaben zum Gen
rat ... Il18(29197)
Biochem./physiol. Wirkung
Interleukin 18, also known as interferon-γ-inducing factor (IGIF) and IL-1γ, is a proinflammatory cytokine. It is an inducer of IFN-γ and Th1 (T cell helper type 1) responses (cell differentiation, cell-mediated cytotoxicity and inflammation). IL-18 induces the migration of microvascular endothelial cells.
Physikalische Form
Lyophilized from 20 mM Tris , 500 mM NaCl, 0.5 mM EDTA, 1 mM TCEP, 0.05% (w/v) PEG8000 pH 8.0 with 5% Trehalose,and 50 μg BSA per μg IL-18
Hinweis zur Analyse
The biological activity is measured by its ability to induce mouse IFN-γ production by activated mouse T cells.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Hier finden Sie alle aktuellen Versionen:
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Weiyi He et al.
Cytokine, 68(1), 32-39 (2014-05-03)
CD4(+) T cell polarization plays a critical role in the pathogenesis of allergy. How to modulate the skewed CD4(+) T cell polarization is less clear. The specific immunotherapy (SIT) is the only specific remedy for the treatment of allergic diseases;
M Dagenais et al.
Mucosal immunology, 9(1), 146-158 (2015-06-04)
Cellular inhibitors of apoptosis proteins (cIAPs) are critical arbiters of cell death and key mediators of inflammation and innate immunity. cIAP2 is frequently overexpressed in colorectal cancer and in regenerating crypts of ulcerative colitis patients. However, its corresponding functions in
Camille Guillerey et al.
Oncoimmunology, 4(9), e1027468-e1027468 (2015-09-26)
The Toll-like receptor 3 (TLR3) agonist poly(I:C) is a promising adjuvant for cancer vaccines due to its induction of potent antitumor responses occurring primarily through the activation of dendritic cells (DCs) and natural killer (NK) cells. However, little is known
Jochem W van der Veen et al.
Regulatory toxicology and pharmacology : RTP, 69(3), 371-379 (2014-05-13)
The currently available animal-free methods for the detection of skin sensitizing potential of chemicals seem promising. However, no single method is able to comprehensively represent the complexity of the processes involved in skin sensitization. To ensure a mechanistic basis and
Anders Elm Pedersen et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 123(7), 547-555 (2015-04-25)
TL1A is a TNF-like cytokine which has been shown to co-stimulate TH1 and TH17 responses during chronic inflammation. The expression of this novel cytokine has been investigated in inflammatory disorders like rheumatoid arthritis and inflammatory bowel disease, but little is
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
Setzen Sie sich mit dem technischen Dienst in Verbindung.