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H9149

Sigma-Aldrich

α-Hydroxyalprazolam

powder, ≥98% (TLC)

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About This Item

Empirische Formel (Hill-System):
C17H13ClN4O
CAS-Nummer:
37115-43-8
Molekulargewicht:
324.76
MDL-Nummer:
MFCD00171226
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24895845
NACRES:
NA.77

Qualitätsniveau

200

Assay

≥98% (TLC)

Form

powder

drug control

Home Office Schedule 4.1; regulated under CDSA - not available from Sigma-Aldrich Canada

Farbe

white to off-white

Löslichkeit

methylene chloride: ~20 mg/mL, clear, colorless to faintly yellow

SMILES String

OCc1nnc2CN=C(c3ccccc3)c4cc(Cl)ccc4-n12

InChI

1S/C17H13ClN4O/c18-12-6-7-14-13(8-12)17(11-4-2-1-3-5-11)19-9-15-20-21-16(10-23)22(14)15/h1-8,23H,9-10H2

InChIKey

ZURUZYHEEMDQBU-UHFFFAOYSA-N

Vorsicht

store dessicated and protected from light

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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α-Hydroxyalprazolam-d5 -Lösung 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Supelco

A-904

α-Hydroxyalprazolam-d5 -Lösung

(±)-Lorazepam

Sigma-Aldrich

L1764

(±)-Lorazepam

L-655,708 ≥98% (HPLC), powder

Sigma-Aldrich

L9787

L-655,708

7-Aminoclonazepam -Lösung 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Supelco

A-915

7-Aminoclonazepam -Lösung

R B Smith et al.
Psychopharmacology, 93(1), 105-112 (1987-01-01)
The relationships between alprazolam and metabolite concentrations and CNS effects were determined in a double-blind placebo controlled four-way crossover trial in 16 normal male volunteers. Active drug treatments consisted of 4-day regimens of 4 mg alprazolam PO daily as 2
Einosuke Tanaka et al.
Journal of forensic and legal medicine, 14(6), 348-351 (2007-07-17)
Alprazolam is widely used as a short-acting antidepressant and anxiolytic agent and its effect appears at very low doses while ethanol is used as a social drug worldwide. Sometimes, toxic interactions occur following combined administration of these two drugs. In
Hadi Molanaei et al.
European journal of clinical pharmacology, 68(5), 571-577 (2011-12-14)
To investigate the impact of persistent inflammation in hemodialysis (HD) patients on the pharmacokinetics of alprazolam, a cytochrome P450 (CYP) 3A4 substrate, and its metabolites and the role of HD in the impact of persistent inflammation in this clinical context.
Casey Jl Johnson et al.
Bioanalysis, 3(20), 2303-2310 (2011-10-21)
Conventional liquid-handling devices were employed, along with an improved punching device, to semi-automate dried blood spot (DBS) extraction of alprazolam, α-hydroxyalprazolam and midazolam from human whole blood. Liquid-handling devices were used to add internal standard to the DBS cards and
A D Fraser et al.
Journal of analytical toxicology, 17(7), 427-431 (1993-11-01)
Adinazolam is a triazolobenzodiazepine, currently under clinical investigation, that possesses antidepressant and anxiolytic activity. It has a short half-life (less than 3 h), and less than 2% of an oral dose is excreted unchanged. The major urinary metabolite is N-desmethyladinazolam
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