H4890

Anti-Human Hemoglobin antibody produced in rabbit

whole antiserum

• MDL-Nummer: MFCD00162411
• UNSPSC-Code: 12352203
• NACRES: NA.43

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 200
• Konjugat: unconjugated
• Antikörperform: whole antiserum
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Enthält: 15 mM sodium azide
• Speziesreaktivität: human
• Methode(n): indirect ELISA: 1:8,000
• UniProt-Hinterlegungsnummer: P68871
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... HBB(3043)

Beschreibung

Allgemeine Beschreibung

HBB (hemoglobin subunit β) codes for a β globin that consists of three exons. This gene is located on human chromosome 11p15. HBB is a serum protein that belongs to the histone-like protein family.

Immunogen

Hemoglobin isolated from normal adult human red blood cells and treated to remove lipoproteins.

Anwendung

Anti-Human Hemoglobin antibody has been used in pulse chase experiments and western blotting.

Anti-Human Hemoglobin antibody produced in rabbit was used for immunoblotting using crude human cerebellar protein extracts and membrane extracts of human RBC. It was used for immunohistochemistry of human tongue cancer samples.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Biochem./physiol. Wirkung

HBB (hemoglobin subunit β) participates in oxygen transport from the lung to various peripheral tissues. Mutation in HBB result in Sickle cell disease (SCD). Overexpression of HBB has been observed in patients with periodontal disease.

Hemoglobin (Hb) is oxygen-binding metalloprotein that is present in the red blood cells. The most abundant Hb is HbA tetramer that is made up of two α, two β chains and the nonprotein heme group. The heme group contains iron ion and a porphyrin ring. Mutations in Hb gene result in hemoglobinopathies, the best known being sickle-cell disease and thalassemias.

Angaben zur Herstellung

treated to remove lipoproteins

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable