GS38

GST T1-1, Recombinant Rat

• Synonym(e): AI255817: glutathione S-transferase, glutathione S-transferase, theta 1, Gstt1-1
• UNSPSC-Code: 12352200
• NACRES: NA.26

Eigenschaften

• Biologische Quelle: rat
• Qualitätsniveau: 100
• Rekombinant: expressed in E. coli
• Assay: >95% (SDS-PAGE)
• Form: frozen liquid
• Spezifische Aktivität: 86.6
• Mol-Gew.: 25 kDa
• Konzentration: 1.22 mg/mL
• Lagertemp.: −70°C
• Angaben zum Gen: rat ... Gstt1(14871)

Beschreibung

Allgemeine Beschreibung

using spectrophotometric determination of 1,2-epoxy-3(4-nitrophenoxy)propane (ENPP) conjugation with reduced glutathione (5 mM) in 100 mM NaPO4 (pH 6.5) at room temperature.

Biochem./physiol. Wirkung

Glutathione S-transferase theta 1 (Gstt1) is an enzyme that in rats is encoded by the Gstt1 gene. Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The GSTs are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Lagerung und Haltbarkeit

The enzyme should be used by the end-user customer within 1 year of receipt.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable