G5502

Guajacol

oxidation indicator

• Synonym(e): 2-Methoxyphenol, Methylcatechol, Pyrocatechol-Monomethylether
• Lineare Formel: (CH₃O)C₆H₄OH
• CAS-Nummer: 90-05-1
• Molekulargewicht: 124.14
• Beilstein: 508112
• EG-Nummer: 201-964-7
• MDL-Nummer: MFCD00002185
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 24895212
• NACRES: NA.77

Eigenschaften

• Dampfdichte: 4.27 (vs air)
• Qualitätsniveau: 100
• Dampfdruck: 0.11 mmHg ( 25 °C)
• Assay: ≥98.0%
• Form: liquid; solid
• Brechungsindex: n20/D 1.543 (lit.)
• bp: 205 °C (lit.)
• mp (Schmelzpunkt): 26-29 °C (lit.)
• Dichte: 1.129 g/mL at 25 °C (lit.)
• SMILES String: COc1ccccc1O
• InChI: 1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3
• InChIKey: LHGVFZTZFXWLCP-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Guaiacol, a phenolic compound, acts as a scavenger of superoxide radicals. It is produced from guaiacum or wood creosote. Guaiacol acts as a precursor to different favoring agents like, vanillin and roasted coffee. It is used as an antiseptic, analgesic and sedative drug for the treatment of dental pulp and periodontal tissue. Guaiacol enhances cell proliferation in vivo.

Anwendung

Guaiacol has been used:

• as a substrate for peroxidase enzyme to determine its activity
• as a substrate to determine laccase activity
• as a reagent in peroxidase (POD) activity test

Biochem./physiol. Wirkung

Guajakol, zusammen mit 2,4,6-Trichlor-anisol, ist verantwortlich für den Korkgeschmack von Wein. Es wurde eine Methode zur Extraktion und Quantifizierung der beiden Verbindungen entwickelt.

Guaiacol has an ability to inhibit prostaglandin biosynthesis, without causing damage to the gastrointestinal system, unlike classic NSAID (nonsteroidal anti-inflammatory drugs).

Vorsicht

May be liquid at room temperature.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319
• P-Sätze: P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): 194.0 °F - closed cup
• Flammpunkt (°C): 90 °C - closed cup
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves