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G3882

Sigma-Aldrich

Gly-Gly-Gly-Gly

≥98% (TLC)

Synonym(e):

Glycyl-glycyl-glycyl-glycin, Tetraglycin, Triglycyl-glycin

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About This Item

Lineare Formel:
NH2CH2CO(NHCH2CO)3OH
CAS-Nummer:
637-84-3
Molekulargewicht:
246.22
Beilstein:
1715387
EG-Nummer:
211-303-4
MDL-Nummer:
MFCD00008129
UNSPSC-Code:
12352209
PubChem Substanz-ID:
24895140
NACRES:
NA.26

product name

Gly-Gly-Gly-Gly,

Assay

≥98% (TLC)

Form

powder

Farbe

white to off-white

mp (Schmelzpunkt)

300 °C

Anwendung(en)

peptide synthesis

Lagertemp.

−20°C

SMILES String

NCC(=O)NCC(=O)NCC(=O)NCC(O)=O

InChI

1S/C8H14N4O5/c9-1-5(13)10-2-6(14)11-3-7(15)12-4-8(16)17/h1-4,9H2,(H,10,13)(H,11,14)(H,12,15)(H,16,17)

InChIKey

QMOQBVOBWVNSNO-UHFFFAOYSA-N

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Amino Acid Sequence

Gly-Gly-Gly-Gly

Biochem./physiol. Wirkung

Tetraglycine is used with copper (Cu-II) to study mechanisms of hydrogen peroxide/bicarbonate free radical production and effect in vitro.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Emerging microbes & infections, 8(1), 45-54 (2019-03-15)
Current influenza vaccines provide hemagglutinin strain-specific protection, but rarely provide cross-protection against divergent strains. It is, therefore, particularly important to develop a universal vaccine against conserved proteins or conserved regions of the virus. In this study, we used N-terminal extracellular
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ChemMedChem, 15(10), 839-850 (2020-03-03)
Staphylococcus aureus is one of the most frequent causes of nosocomial and community-acquired infections, with drug-resistant strains being responsible for tens of thousands of deaths per year. S. aureus sortase A inhibitors are designed to interfere with virulence determinants. We
J I Vandenberg et al.
Biochimica et biophysica acta, 846(1), 127-134 (1985-07-30)
Evidence is presented that tripeptides enter human erythrocytes via saturable transport system(s) at rates similar to those previously described for dipeptides (King, G.F. and Kuchel, P.W. (1985) Biochem. J. 227, 833-842) but that the transmembrane flux rates for tetrapeptides are
Ruben G M Moreno et al.
Journal of inorganic biochemistry, 101(5), 866-875 (2007-03-27)
S(IV) (SO(2),HSO(3)(-)andSO(3)(2-)) autoxidation catalyzed by Cu(II)/tetraglycine complexes in the presence of DNA or 2'-deoxyguanosine (dGuo) resulted in DNA strand breaks and formation of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo), respectively. Ni(II), Co(II) or Mn(II) (1.0x10(-4)M) complexes had much smaller effects. Cu(II)/tetraglycine (1.0x10(-4)M) in the
Evgenyi Shalaev et al.
Journal of pharmaceutical sciences, 91(2), 584-593 (2002-02-09)
Many drugs undergo chemical changes in the solid state, and understanding chemical reactivity of organic crystals is a critical factor in the drug development process. In this report, the impact of milling on the thermal chemical reactivity of an organic
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