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Merck

G1260

Sigma-Aldrich

Gastrin II Sulfated

≥95% (HPLC), suitable for ligand binding assays

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

Empirische Formel (Hill-System):
C97H124N20O34S2
CAS-Nummer:
Molekulargewicht:
2178.27
MDL-Nummer:
UNSPSC-Code:
12352209
PubChem Substanz-ID:
NACRES:
NA.26

product name

Gastrin II Sulfated, ≥95% (HPLC)

Qualitätsniveau

Assay

≥95% (HPLC)

Form

powder

Methode(n)

ligand binding assay: suitable

Farbe

white

UniProt-Hinterlegungsnummer

Lagertemp.

−20°C

SMILES String

CSCCC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)C(Cc3ccc(OS(O)(=O)=O)cc3)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(Cc4c[nH]c5ccccc45)NC(=O)C6CCCN6C(=O)CNC(=O)C7CCC(=O)N7)C(=O)NC(CC(O)=O)C(=O)NC(Cc8ccccc8)C(N)=O

InChI

1S/C97H124N20O34S2/c1-49(2)39-68(114-95(145)71(43-54-46-100-59-18-11-9-16-57(54)59)116-97(147)73-19-12-37-117(73)76(120)48-102-85(135)60-24-30-74(118)104-60)93(143)110-65(29-35-81(129)130)91(141)109-64(28-34-80(127)128)90(140)108-63(27-33-79(125)126)89(139)107-62(26-32-78(123)124)88(138)106-61(25-31-77(121)122)87(137)103-50(3)84(134)113-69(41-52-20-22-55(23-21-52)151-153(148,149)150)86(136)101-47-75(119)105-70(42-53-45-99-58-17-10-8-15-56(53)58)94(144)111-66(36-38-152-4)92(142)115-72(44-82(131)132)96(146)112-67(83(98)133)40-51-13-6-5-7-14-51/h5-11,13-18,20-23,45-46,49-50,60-73,99-100H,12,19,24-44,47-48H2,1-4H3,(H2,98,133)(H,101,136)(H,102,135)(H,103,137)(H,104,118)(H,105,119)(H,106,138)(H,107,139)(H,108,140)(H,109,141)(H,110,143)(H,111,144)(H,112,146)(H,113,134)(H,114,145)(H,115,142)(H,116,147)(H,121,122)(H,123,124)(H,125,126)(H,127,128)(H,129,130)(H,131,132)(H,148,149,150)

InChIKey

WSLIFCVCCVWYQQ-UHFFFAOYSA-N

Angaben zum Gen

human ... GAST(2520)

Amino Acid Sequence

pGlu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr(SO3H)-Gly-Trp-Met-Asp-Phe-NH2

Biochem./physiol. Wirkung

Gastrin II and Gastrin I are peptide hormones involved in gastrointestinal processes such as the stimulation of gastric (HCl) release.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Die Dokumentenbibliothek aufrufen

T Sethi et al.
Cancer research, 52(21), 6031-6035 (1992-11-01)
Gastrin has been postulated to be a physiological growth factor, but compelling in vitro evidence of this has been difficult to obtain. In the present study we investigated whether small cell lung carcinoma cell lines could provide a useful model
I Gede Arinton
Acta medica Indonesiana, 42(3), 142-146 (2010-08-21)
to find out biomarker as diagnostic tool of H. pylori chronic gastritis. the design of present study was a diagnostic test and there were 104 subjects with H. pylori chronic gastritis who fulfilled the inclusion and exclusion criteria. The diagnosis
Saroj Kumari et al.
Chembiochem : a European journal of chemical biology, 13(2), 282-292 (2011-12-14)
Fluorescent labeling has enabled a better understanding of the relationships between receptor location, function, and life cycle. Each of these perspectives contributes new insights into drug action, particularly for G protein-coupled receptors (GPCRs). The aim of this study was to
A Botella et al.
Gastroenterology, 102(3), 779-786 (1992-03-01)
The aim of this study was to determine the cholecystokinin (CCK) receptor subtype involved in the direct myogenic effect of CCK on pig ileum. Smooth muscle cells were dispersed from pig ileum circular muscle layer and incubated in the presence
K Kitagawa et al.
Chemical & pharmaceutical bulletin, 49(8), 958-963 (2001-08-23)
Application of the fluoren-9-ylmethoxycarbonyl (Fmoc)-based solid-phase segment condensation approach to the preparation of sulfated peptides was investigated through the synthesis of human big gastrin-II, a 34-residue sulfated tyrosine [Tyr(SO3H)]-containing peptide. Highly acid-sensitive 2-chlorotrityl resin (Clt resin) was exclusively employed as

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