G0541

Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert N1) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

• MDL-Nummer: MFCD02096429
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: lyophilized powder
• Mol-Gew.: antigen 100 kDa
• Speziesreaktivität: rat
• Verpackung: antibody small pack of 25 μg
• Methode(n): dot blot: 1:1000; immunohistochemistry: 1:1000; western blot: 1:1000
• UniProt-Hinterlegungsnummer: P35439
• Lagertemp.: 2-8°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: rat ... Grin1(24408)

Beschreibung

Immunogen

synthetic peptide representing the sequence of the N1 splice variant.

Anwendung

Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert N1) antibody is suitable for dot blot, immunohistochemistry and western blot at a dilution of 1:1000.

Biochem./physiol. Wirkung

NMDA receptors (NMDAR) are glutamate-gated ion channels. It is sensitive to N-methyl-D-aspartate (NMDA) and consists of several homologous subunits (NMDAR1). NMDAR is highly expressed in the central nervous system and involved in excitatory synaptic transmission as well as synaptic plasticity. The activity of NMDA receptors are modulated by glycine. It exhibits high calcium permeability and unique voltage-dependent sensitivity to magnesium. It has been reported that phosphorylated NMDA receptors may regulate their function and play a role in many forms of synaptic plasticity such as long-term potentiation.

Physikalische Form

Lyophilized powder from 5 mM ammonium bicarbonate (some residual salt may be present)

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable