FLAAS

Adenosine 5′-triphosphate (ATP) disodium salt hydrate

vial of ~1 mg ATP

• Synonym(e): ATP Dinatrium Hydrat
• Lineare Formel: C₁₀H₁₄N₅O₁₃P₃Na₂ · xH₂O
• CAS-Nummer: 34369-07-8
• Molekulargewicht: 551.14 (anhydrous basis)
• EG-Nummer: 213-579-1
• MDL-Nummer: MFCD00150755
• UNSPSC-Code: 12352202
• eCl@ss: 32160414
• PubChem Substanz-ID: 24895005
• NACRES: NA.26

Eigenschaften

• Biologische Quelle: bacterial (Corynebacterium sp)
• Qualitätsniveau: 200
• Assay: ≥90%
• Form: lyophilized powder
• Verpackung: vial of ~1 mg ATP
• Lagertemp.: −20°C
• SMILES String: Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• InChIKey: NTBQNWBHIXNPRU-MSQVLRTGSA-L

Beschreibung

Anwendung

Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been:

• used as a standard to measure ATP by bioluminescence method
• used in kinase buffer to assess the interaction between death-associated protein kinases (DAPK2) and 14-3-3-β
• used as a standard in ATP colorimetric assay

Biochem./physiol. Wirkung

P₂ purinergener Antagonist; erhöht die Aktivität von Ca²⁺-aktivierten K⁺ Kanälen; Substrat für ATP-abhängigen Enzymsysteme.

Adenosine 5′-triphosphate (ATP) is one of the nucleoside triphosphate present in living system. It controls various biologic processes such as glucose metabolism, muscle contraction and neurotransmission. Apart from this, ATP serves as an important energy source for the cell. Administration of ATP might be useful in the treatment of non-small-cell lung cancer.

Adenosine 5′-triphosphate was shown to have inhibitory effects on the inflammatory response by abrogating secretion of TNF-α and promoting secretion of Interleukin-10.

Menge

Each vial contains ~1.2 mg of Na₂ATP • 3H₂O equivalent to ~1.0 mg of ATP (2.0 μmol). Actual amount printed on the label.

Angaben zur Herstellung

Prepared to be substantially vanadium-free.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)